Bananflugans genetiska nätverk, filmat

One of the major goals in biology is to reconstruct the complex\ngenetic networks that operate inside cells, and to \"film\" how these\nnetworks evolve during the course of an organism's development.

Today, Eric Xing and buddies at Carnegie Mellon University in\nPittsburgh claim to have worked out how the way patterns of gene\nexpression change in fruitflies over the course of their entire\ndevelopment. That's a world first and no mean feat to boot.

Från abstract:

Using a new machine learning method called\nTesla, which builds on a novel temporal logistic regression technique, we\nreport the first successful genome-wide reverse-engineering of the latent\nsequence of temporally rewiring gene networks over more than 4000 genes during\nthe life cycle of Drosophila melanogaster, given longitudinal gene\nexpression measurements and even when a single snapshot of such measurement\nresulted from each (time-specific) network is available.